Environmental photochemistry of fenamate NSAIDs and their radical intermediates
نویسندگان
چکیده
منابع مشابه
Quinone methide intermediates in organic photochemistry*
Quinone methides are widely encountered reactive intermediates in the chemistry of phenols and related compounds. This paper summarizes our recent progress in uncovering new and general photochemical methods for forming quinone methides of various structural types in aqueous solution. Their mechanism of formation and subsequent chemistry are also discussed. New examples of excited-state intramo...
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چکیده ندارد.
15 صفحه اولFenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase-1 (COX-1) and COX-2 enzymes. The NLRP3 inflammasome is a multi-protein complex responsible for the processing of the proinflammatory cytokine interleukin-1β and is implicated in many inflammatory diseases. Here we show that several clinically approved and widely used NSAIDs of the fenamate class are effective and selective in...
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Free radicals intermediates are formed on the surface of metal oxide semiconductors, namely Ti02 and Fe203, following the light-induced charge separation upon band-gap illu-mination. These radicals appear to adhere strongly to the ~.urfaces of the small colloidal particles (diameters between 5 and 20 nm) employed in this study. A second electron-transfer step yielding the observed end-products ...
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The photochemical behaviour of the herbicide napropamide is studied on cellulose and silica surfaces, using steady-state and laser-flash diffuse reflectance techniques. The results are used to probe how the reaction sites of the host matrices influence the photo-reactive pathways. Napropamide undergoes reaction when irradiated with UV (lamps) or visible (sunlight) radiation on both solid suppor...
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ژورنال
عنوان ژورنال: Environmental Science: Processes & Impacts
سال: 2017
ISSN: 2050-7887,2050-7895
DOI: 10.1039/c7em00079k